Sweet Jimmy Mac I knew you had it in you. Variety reported today that James McAvoy has signed on to star in comedic adaptation of the Will Reiser novel “I’m With Cancer.” Nicole Holofcener will direct, and the pic will co-star Seth Rogen, who is also producing.

In the first major project McAvoy has agreed to star in since the Universal comicbook actioner “Wanted” and its upcoming sequel, he will play a 25-year-old who learns he has cancer and successfully battles the disease over several years.

After watching the BBC’s Shameless in which McAvoy costarred, I can honestly say that while he is a gorgeous stallion of a man with a 10,000 yard deathsex stare, he does have comedic chops. The pairing of these two shall be monumental and rank rather highly on the Danger Bowie spank it meter. Seth Rogen is unstoppable. I can’t wait to see who’ll he co star with next. Perhaps if the powers that be hear my eternal cries, we can expect Pineapple Express 2 with Brad Pitt joining the cast as Gary Cole’s long lost brother, who is fresh out of prison and wants to avenge his late brother death. Coming at you in 2013. One can always dream.